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Saxagliptin Hydrochloride

CHEMBL1201743 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
351.9 g/mol
LogP
—
Phase
4

Saxagliptin hydrochloride is the hydrochloride salt of saxagliptin, a selective DPP-4 inhibitor that prolongs the activity of incretin hormones GLP-1 and GIP to stimulate glucose-dependent insulin secretion and suppress glucagon in type 2 diabetes. By inhibiting DPP-4, it prevents rapid degradation of endogenous incretins, enhancing postprandial glucose control with a low risk of hypoglycemia. It is used as monotherapy or in combination with other antidiabetic agents.

Молекулярная масса

351,9000 g/mol

TPSA

90,40 Ų

Терапевтические области

Type 2 Diabetes

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Cl.N#C[C@@H]1C[C@@H]2C[C@@H]2N1C(=O)[C@@H](N)C12CC3CC(CC(O)(C3)C1)C2

                

                

                
                

                    
InChI

                    
InChI=1S/C18H25N3O2.ClH/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17;/h10-15,23H,1-7,9,20H2;1H/t10?,11?,12-,13+,14+,15-,17?,18?;/m1./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C18H26ClN3O2

                    

                    
                    

                        
HBD / HBA

                        
3 / 4

                    

                    
                    

                        
Вращаемые Связи

                        
2

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
24

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
Saxagliptin hydrochloride is the hydrochloride salt of saxagliptin, a selective DPP-4 inhibitor that prolongs the activity of incretin hormones GLP-1 and GIP to stimulate glucose-dependent insulin secretion and suppress glucagon in type 2 diabetes. By inhibiting DPP-4, it prevents rapid degradation of endogenous incretins, enhancing postprandial glucose control with a low risk of hypoglycemia. It is used as monotherapy or in combination with other antidiabetic agents.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Saxagliptin Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1201743.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 49800073.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.