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Telmisartan

CHEMBL1017 Phase 4 Disetujui Small molecule
Half-Life
24 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
514.6 g/mol
LogP
6.9
Phase
4

This medication belongs to the angiotensin receptor blocker (ARB) class and is used to treat high blood pressure and to reduce the risk of heart attack and stroke in high-risk patients. It works by blocking the action of a hormone called angiotensin II, which normally tightens blood vessels. It is taken once daily and is generally well tolerated.

Berat Molekul

514,6230 g/mol

LogP

6,90

TPSA

72,90 Ų

Lipinski RO5

Gagal

Area Terapeutik

Ovarian Cancer Cardiovascular Disease Alzheimer's Disease Parkinson's Disease Schizophrenia Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Stroke Hyperlipidemia Obesity Type 2 Diabetes Hypertension Breast Cancer Heart Failure Atrial Fibrillation Prostate Cancer

Kelas Obat

C — C - Cardiovascular System

Mekanisme Kerja

Selective angiotensin II type 1 receptor antagonist; also a partial PPAR-gamma agonist.

Pharmacokinetics (PK)

Half-Life 24 hours

Pharmacodynamics (PD)

Mekanisme

Selective angiotensin II type 1 receptor antagonist; also a partial PPAR-gamma agonist.

Struktur 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCCc1nc2c(C)cc(-c3nc4ccccc4n3C)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1

                

                

                
                

                    
InChI

                    
InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)

                

                

                

                    
                    

                        
Molecular Formula

                        
C33H30N4O2

                    

                    
                    

                        
HBD / HBA

                        
1 / 4

                    

                    
                    

                        
Ikatan yang Dapat Dirotasi

                        
7

                    

                    
                    
                    

                        
Atom Berat

                        
39

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Pertanyaan yang Sering Diajukan

                

                    
                    

                        
                        

                            
This medication belongs to the angiotensin receptor blocker (ARB) class and is used to treat high blood pressure and to reduce the risk of heart attack and stroke in high-risk patients. It works by blocking the action of a hormone called angiotensin II, which normally tightens blood vessels. It is taken once daily and is generally well tolerated.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Selective angiotensin II type 1 receptor antagonist; also a partial PPAR-gamma agonist.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Telmisartan: Half-life: 24 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Telmisartan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            
            

                
Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
                            Atorvastatin
                            Small molecule
                        
                        
                        
                            Amlodipine
                            Small molecule
                        
                        
                        
                            Lisinopril
                            Small molecule
                        
                        
                        
                            Metoprolol
                            Small molecule
                        
                        
                    

                

                

                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1017.
                Open-access bioactivity database.
            
        
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  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 65999.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Penyangkalan Medis

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.