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Treprostinil Diolamine

CHEMBL2107815 Phase 4 Disetujui Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
495.6 g/mol
LogP
—
Phase
4

Treprostinil diolamine is the diolamine salt form of treprostinil, a prostacyclin receptor agonist used for pulmonary arterial hypertension. See treprostinil for complete pharmacological details. This salt formulation is used in oral extended-release tablet preparations for PAH management in heart failure and hypertension contexts.

Berat Molekul

495,6000 g/mol

TPSA

139,00 Ų

Area Terapeutik

Hypertension Heart Failure

Mekanisme Kerja

Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

Struktur 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCCCC[C@H](O)CC[C@@H]1[C@H]2Cc3cccc(OCC(=O)O)c3C[C@H]2C[C@H]1O.OCCNCCO

                

                

                
                

                    
InChI

                    
InChI=1S/C23H34O5.C4H11NO2/c1-2-3-4-7-17(24)9-10-18-19-11-15-6-5-8-22(28-14-23(26)27)20(15)12-16(19)13-21(18)25;6-3-1-5-2-4-7/h5-6,8,16-19,21,24-25H,2-4,7,9-14H2,1H3,(H,26,27);5-7H,1-4H2/t16-,17-,18+,19-,21+;/m0./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C27H45NO7

                    

                    
                    

                        
HBD / HBA

                        
6 / 8

                    

                    
                    

                        
Ikatan yang Dapat Dirotasi

                        
14

                    

                    
                    
                    

                        
Atom Berat

                        
35

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Pertanyaan yang Sering Diajukan

                

                    
                    

                        
                        

                            
Treprostinil diolamine is the diolamine salt form of treprostinil, a prostacyclin receptor agonist used for pulmonary arterial hypertension. See treprostinil for complete pharmacological details. This salt formulation is used in oral extended-release tablet preparations for PAH management in heart failure and hypertension contexts.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Treprostinil Diolamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2107815.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 11179459.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Penyangkalan Medis

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.