Veratrum Viride Root

CHEMBL1201531 Phase 4 Disetujui Unknown

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

— g/mol

LogP

—

Phase

4

Veratrum viride (American hellebore) root contains steroidal alkaloids (jervine, veratrine, cyclopamine) that activate and then block voltage-gated sodium channels in cardiac and vascular tissue, producing bradycardia and hypotension. Historically, extracts were used as antihypertensive agents before modern therapies, but the narrow therapeutic window and potential for severe toxicity limited clinical use. Cyclopamine, derived from Veratrum californicum, has become important in cancer research as a Hedgehog pathway inhibitor.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

Veratrum viride (American hellebore) root contains steroidal alkaloids (jervine, veratrine, cyclopamine) that activate and then block voltage-gated sodium channels in cardiac and vascular tissue, producing bradycardia and hypotension. Historically, extracts were used as antihypertensive agents before modern therapies, but the narrow therapeutic window and potential for severe toxicity limited clinical use. Cyclopamine, derived from Veratrum californicum, has become important in cancer research as a Hedgehog pathway inhibitor.

Yes, Veratrum Viride Root is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.

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References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201531. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

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Data Cepat

Sinonim: 2

Tautan Eksternal

ChEMBL CHEMBL1201531

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.