Chirality
The property of a molecule that is non-superimposable on its mirror image. Enantiomers can have dramatically different pharmacological activity, potency, and toxicity profiles.
Contoh
- S-omeprazole (esomeprazole)
- R/S-warfarin (different potency)
- Thalidomide (R-sedative, S-teratogenic)
Tahukah Anda?
The property of a molecule that is non-superimposable on its mirror image. Enantiomers can have dramatically different pharmacological activity, potency, and toxicity profiles.