Tachyphylaxis

Pharmacodynamics

Rapid decrease in drug response after repeated administration over a short period. Distinguished from tolerance by its acute onset. Often involves depletion of neurotransmitter stores.

Contoh

  • Indirect sympathomimetics (ephedrine)
  • Nitrate tolerance
  • Nicotine (acute)

Tahukah Anda?

Rapid decrease in drug response after repeated administration over a short period. Distinguished from tolerance by its acute onset. Often involves depletion of neurotransmitter stores.