DRD2 (Dopamine D2 Receptor)
DRD2
G-protein coupled receptor (Gi/o) mediating dopaminergic neurotransmission.
Fungsi
Key target for antipsychotic drugs (antagonists) and anti-parkinsonian agents (agonists). D2 blockade in the mesolimbic pathway reduces positive psychotic symptoms.
Obat yang Bekerja pada Target Ini
| Obat | Aksi | Utama |
|---|---|---|
| Levodopa | Agonist | Ya |
| Quetiapine | Antagonist | Ya |
| Aripiprazole | Partial Agonist | Ya |
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