SCN9A (Sodium Channel Nav1.7)
SCN9A
Voltage-gated sodium channel preferentially expressed in nociceptive neurons.
Fungsi
Gain-of-function mutations cause inherited pain disorders. Blocking reduces pain signaling.
Obat yang Bekerja pada Target Ini
| Obat | Aksi | Utama |
|---|---|---|
| Valproic Acid | Blocker | Ya |
| Topiramate | Blocker | Ya |
| Phenytoin | Blocker | Ya |
| Gabapentin | Blocker | Ya |
| Pregabalin | Blocker | Ya |
| Lamotrigine | Blocker | Ya |
| Carbamazepine | Blocker | Ya |
| Furosemide | Inhibitor | Ya |
| Hydrochlorothiazide | Inhibitor | Ya |