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Aminopyrine

CHEMBL288470 Phase 4 承認済み Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
231.3 g/mol
LogP
1.0
Phase
4

An analgesic and antipyretic drug that reduces pain and fever by inhibiting prostaglandin synthesis, once widely used but now largely abandoned because of its ability to cause agranulocytosis, a dangerous depletion of white blood cells. It has been replaced by safer alternatives like paracetamol and ibuprofen.

分子量

231.2900 g/mol

LogP

1.00

TPSA

26.80 Ų

リピンスキーの五則

適合

治療領域

Pain Management Migraine Generalized Anxiety Disorder Stroke Gastroenterology Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D構造

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Cc1c(N(C)C)c(=O)n(-c2ccccc2)n1C

                

                

                
                

                    
InChI

                    
InChI=1S/C13H17N3O/c1-10-12(14(2)3)13(17)16(15(10)4)11-8-6-5-7-9-11/h5-9H,1-4H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C13H17N3O

                    

                    
                    

                        
HBD / HBA

                        
- / 3

                    

                    
                    

                        
回転可能結合数

                        
2

                    

                    
                    
                    

                        
重原子数

                        
17

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
よくある質問

                

                    
                    

                        
                        

                            
An analgesic and antipyretic drug that reduces pain and fever by inhibiting prostaglandin synthesis, once widely used but now largely abandoned because of its ability to cause agranulocytosis, a dangerous depletion of white blood cells. It has been replaced by safer alternatives like paracetamol and ibuprofen.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Aminopyrine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL288470.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 6009.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医学的免責事項

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.