Aminopyrine

CHEMBL288470 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

231.3 g/mol

LogP

1.0

Phase

4

An analgesic and antipyretic drug that reduces pain and fever by inhibiting prostaglandin synthesis, once widely used but now largely abandoned because of its ability to cause agranulocytosis, a dangerous depletion of white blood cells. It has been replaced by safer alternatives like paracetamol and ibuprofen.

Molecular Weight

231.2900 g/mol

LogP

1.00

TPSA

26.80 Å²

Lipinski RO5

Pass

Therapeutic Areas

Chronic Pain Gastroenterology Generalized Anxiety Disorder Migraine Pain Management Stroke

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

Cite this structure

Embed this structure

SMILES

Cc1c(N(C)C)c(=O)n(-c2ccccc2)n1C

InChI

InChI=1S/C13H17N3O/c1-10-12(14(2)3)13(17)16(15(10)4)11-8-6-5-7-9-11/h5-9H,1-4H3

Molecular Formula

C13H17N3O

HBD / HBA

- / 3

Rotatable Bonds

2

Heavy Atoms

17

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

An analgesic and antipyretic drug that reduces pain and fever by inhibiting prostaglandin synthesis, once widely used but now largely abandoned because of its ability to cause agranulocytosis, a dangerous depletion of white blood cells. It has been replaced by safer alternatives like paracetamol and ibuprofen.

Yes, Aminopyrine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL288470. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6009. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

Looking for patient-friendly information?

Aminopyrine on PillFYI

Structure

Quick Data

Formula: C13H17N3O

External Links

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.