Cidofovir

CHEMBL5314375 Phase 4 承認済み Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

279.2 g/mol

LogP

-3.6

Phase

4

An antiviral nucleotide analog that inhibits viral DNA polymerase, used intravenously for cytomegalovirus (CMV) retinitis in patients with AIDS when other antivirals are contraindicated. Serious nephrotoxicity is the major dose-limiting toxicity, requiring co-administration of probenecid and aggressive intravenous hydration to reduce kidney damage. It is reserved for refractory or intolerant cases due to its toxicity profile.

分子量

279.1900 g/mol

LogP

-3.60

TPSA

146.00 Å²

リピンスキーの五則

適合

治療領域

Pain Management Epilepsy Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Chronic Kidney Disease Hypertension Chronic Pain HIV/AIDS Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D構造

SVG PNG

Cite this structure

Embed this structure

SMILES

Nc1ccn(C[C@@H](CO)OCP(=O)(O)O)c(=O)n1.O.O

InChI

InChI=1S/C8H14N3O6P.2H2O/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16;;/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16);2*1H2/t6-;;/m0../s1

Molecular Formula

C8H14N3O6P

HBD / HBA

4 / 6

回転可能結合数

6

重原子数

18

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

An antiviral nucleotide analog that inhibits viral DNA polymerase, used intravenously for cytomegalovirus (CMV) retinitis in patients with AIDS when other antivirals are contraindicated. Serious nephrotoxicity is the major dose-limiting toxicity, requiring co-administration of probenecid and aggressive intravenous hydration to reduce kidney damage. It is reserved for refractory or intolerant cases due to its toxicity profile.

Yes, Cidofovir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL5314375. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 60613. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

患者向けのわかりやすい情報をお探しですか？

Cidofovir PillFYIで

構造

クイックデータ

分子式: C8H14N3O6P
同義語: 1

外部リンク

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.