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Esketamine

CHEMBL395091 Phase 4 承認済み Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
237.7 g/mol
LogP
2.2
Phase
4

This medication works rapidly on NMDA receptors in the brain to relieve symptoms of severe or treatment-resistant depression. Unlike traditional antidepressants, it can begin to reduce depressive symptoms within hours.

分子量

237.7200 g/mol

LogP

2.20

TPSA

29.10 Ų

リピンスキーの五則

適合

治療領域

Ovarian Cancer Endometriosis Pain Management Parkinson's Disease Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Infectious Disease Obesity Major Depressive Disorder Breast Cancer Chronic Pain Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D構造

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CN[C@]1(c2ccccc2Cl)CCCCC1=O

                

                

                
                

                    
InChI

                    
InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3/t13-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C13H16ClNO

                    

                    
                    

                        
HBD / HBA

                        
1 / 2

                    

                    
                    

                        
回転可能結合数

                        
2

                    

                    
                    
                    

                        
重原子数

                        
16

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
よくある質問

                

                    
                    

                        
                        

                            
This medication works rapidly on NMDA receptors in the brain to relieve symptoms of severe or treatment-resistant depression. Unlike traditional antidepressants, it can begin to reduce depressive symptoms within hours.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Esketamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL395091.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 182137.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医学的免責事項

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.