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Hydroxychloroquine Sulfate

CHEMBL1690 Phase 4 承認済み Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
434.0 g/mol
LogP
—
Phase
4

This is the sulfate salt form of hydroxychloroquine, an antimalarial and immunomodulatory drug used to treat lupus, rheumatoid arthritis, and certain other inflammatory conditions. It works by reducing immune system overactivity and has also been studied experimentally for various other conditions. Periodic eye monitoring is necessary with long-term treatment.

分子量

434.0000 g/mol

TPSA

131.00 Ų

治療領域

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Cardiovascular Disease Age-Related Macular Degeneration Respiratory Disease Dermatology Non-Small Cell Lung Cancer Rheumatoid Arthritis Chronic Obstructive Pulmonary Disease Migraine Generalized Anxiety Disorder Infectious Disease Melanoma Oncology Psoriasis Systemic Lupus Erythematosus Multiple Sclerosis Chronic Kidney Disease Obesity Rheumatology Transplant Medicine Type 2 Diabetes Breast Cancer Atopic Dermatitis Malaria HIV/AIDS Hepatitis C Atrial Fibrillation Prostate Cancer Colorectal Cancer Leukemia

作用機序

Accumulates in lysosomes raising pH; inhibits toll-like receptor signaling.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

機序

Accumulates in lysosomes raising pH; inhibits toll-like receptor signaling.

2D構造

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12.O=S(=O)(O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)

                

                

                

                    
                    

                        
Molecular Formula

                        
C18H28ClN3O5S

                    

                    
                    

                        
HBD / HBA

                        
4 / 8

                    

                    
                    

                        
回転可能結合数

                        
9

                    

                    
                    
                    

                        
重原子数

                        
28

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
よくある質問

                

                    
                    

                        
                        

                            
This is the sulfate salt form of hydroxychloroquine, an antimalarial and immunomodulatory drug used to treat lupus, rheumatoid arthritis, and certain other inflammatory conditions. It works by reducing immune system overactivity and has also been studied experimentally for various other conditions. Periodic eye monitoring is necessary with long-term treatment.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Accumulates in lysosomes raising pH; inhibits toll-like receptor signaling.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Hydroxychloroquine Sulfate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1690.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 12947.
                Chemical information database.
            
        
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Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医学的免責事項

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.