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Norfloxacin

CHEMBL9 Phase 4 承認済み Small molecule
Half-Life
3-4 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
319.3 g/mol
LogP
-1.0
Phase
4

A fluoroquinolone antibiotic used to treat urinary tract infections by stopping bacterial DNA replication.

分子量

319.3310 g/mol

LogP

-1.00

TPSA

72.90 Ų

リピンスキーの五則

適合

治療領域

Hypertension

薬物分類

J — J - Antiinfectives for Systemic Use

作用機序

Second-generation fluoroquinolone inhibiting bacterial DNA gyrase and topoisomerase IV.

Pharmacokinetics (PK)

Half-Life 3-4 hours

Pharmacodynamics (PD)

機序

Second-generation fluoroquinolone inhibiting bacterial DNA gyrase and topoisomerase IV.

2D構造

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21

                

                

                
                

                    
InChI

                    
InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H18FN3O3

                    

                    
                    

                        
HBD / HBA

                        
2 / 7

                    

                    
                    

                        
回転可能結合数

                        
3

                    

                    
                    
                    

                        
重原子数

                        
23

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
よくある質問

                

                    
                    

                        
                        

                            
A fluoroquinolone antibiotic used to treat urinary tract infections by stopping bacterial DNA replication.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Second-generation fluoroquinolone inhibiting bacterial DNA gyrase and topoisomerase IV.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Norfloxacin: Half-life: 3-4 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Norfloxacin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            
            

                
Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
                            Amoxicillin
                            Small molecule
                        
                        
                        
                            Azithromycin
                            Small molecule
                        
                        
                        
                            Ciprofloxacin
                            Small molecule
                        
                        
                        
                            Doxycycline
                            Small molecule
                        
                        
                    

                

                

                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL9.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4539.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
医学的免責事項

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.