Pipobroman

CHEMBL1585 Phase 4 承認済み Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

356.0 g/mol

LogP

0.4

Phase

4

Pipobroman is an alkylating antineoplastic agent structurally related to busulfan that exerts its cytotoxic effects by cross-linking DNA strands, thereby inhibiting DNA replication and inducing cell death in rapidly dividing cells. It has been used in the treatment of polycythemia vera and essential thrombocythemia as a myelosuppressive agent.

分子量

356.0500 g/mol

LogP

0.40

TPSA

40.60 Å²

リピンスキーの五則

適合

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D構造

SVG PNG

Cite this structure

Embed this structure

SMILES

O=C(CCBr)N1CCN(C(=O)CCBr)CC1

InChI

InChI=1S/C10H16Br2N2O2/c11-3-1-9(15)13-5-7-14(8-6-13)10(16)2-4-12/h1-8H2

Molecular Formula

C10H16Br2N2O2

HBD / HBA

- / 2

回転可能結合数

4

重原子数

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

Pipobroman is an alkylating antineoplastic agent structurally related to busulfan that exerts its cytotoxic effects by cross-linking DNA strands, thereby inhibiting DNA replication and inducing cell death in rapidly dividing cells. It has been used in the treatment of polycythemia vera and essential thrombocythemia as a myelosuppressive agent.

Yes, Pipobroman is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1585. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4842. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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構造

クイックデータ

分子式: C10H16Br2N2O2

外部リンク

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医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.