Bioisostere
A chemical substituent or group that mimics the spatial, electronic, or pharmacological properties of another group. Used in medicinal chemistry to optimize drug properties while maintaining biological activity.
例
- F replaces H
- Tetrazole replaces carboxylate
- Thiophene replaces phenyl
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A chemical substituent or group that mimics the spatial, electronic, or pharmacological properties of another group. Used in medicinal chemistry to optimize drug properties while maintaining biological activity.