Enterohepatic Recirculation
The process where a drug excreted in bile is reabsorbed from the intestine back into portal circulation. Creates secondary plasma peaks and prolongs apparent half-life.
例
- Oral contraceptives (antibiotic interaction)
- Mycophenolate
- Diclofenac
ご存知でしたか？
The process where a drug excreted in bile is reabsorbed from the intestine back into portal circulation. Creates secondary plasma peaks and prolongs apparent half-life.