Number Needed to Treat (NNT)

NNT
Clinical

The number of patients who need to be treated with a drug for one additional patient to benefit compared to control. Calculated as 1/absolute risk reduction (ARR). Lower NNT indicates greater clinical benefit.

  • Statins for CVD prevention NNT ~50
  • Antibiotics for UTI NNT ~2
  • Ideal NNT = 1

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The number of patients who need to be treated with a drug for one additional patient to benefit compared to control. Calculated as 1/absolute risk reduction (ARR). Lower NNT indicates …