OPRM1 (Mu-Opioid Receptor)
OPRM1
G-protein coupled receptor (Gi/o) mediating analgesia, euphoria, respiratory depression, and physical dependence.
機能
Primary target for opioid analgesics (morphine, fentanyl, oxycodone). Activation produces potent analgesia but also respiratory depression and addiction.
この標的に作用する薬物
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HRH2 (Histamine H2 Receptor)
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