Bupropion vs Citalopram

## Bupropion vs Citalopram: Overview

This comparison examines the pharmacological differences between **Bupropion** and **Citalopram**.

## Mechanism of Action

**Bupropion**: Norepinephrine-dopamine reuptake inhibitor (NDRI).

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

## Pharmacokinetics

**Half-life**: Bupropion — 21 hours; Citalopram — 35 hours.

## Chemical Properties

**Molecular Formula**: Bupropion — C13H18ClNO; Citalopram — C20H21FN2O.

**Molecular Weight**: Bupropion — 239.7420 g/mol; Citalopram — 324.3920 g/mol.

**Type**: Bupropion — Small molecule; Citalopram — Small molecule.