Citalopram vs Trazodone

## Citalopram vs Trazodone: Overview

This comparison examines the pharmacological differences between **Citalopram** and **Trazodone**.

## Mechanism of Action

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

**Trazodone**: Serotonin antagonist and reuptake inhibitor (SARI).

## Pharmacokinetics

**Half-life**: Citalopram — 35 hours; Trazodone — 5-9 hours.

## Chemical Properties

**Molecular Formula**: Citalopram — C20H21FN2O; Trazodone — C19H22ClN5O.

**Molecular Weight**: Citalopram — 324.3920 g/mol; Trazodone — 371.8640 g/mol.

**Type**: Citalopram — Small molecule; Trazodone — Small molecule.