Guanabenz Acetate

CHEMBL1200560 Phase 4 승인됨 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

291.1 g/mol

LogP

—

Phase

4

The acetate salt form of guanabenz, a centrally acting antihypertensive that reduces blood pressure by stimulating alpha-2 receptors in the brainstem to decrease sympathetic nervous system activity. This formulation is used in oral tablet preparations for managing hypertension. Gradual dose reduction is important when stopping treatment to prevent rebound high blood pressure.

분자량

291.1300 g/mol

TPSA

114.00 Å²

치료 영역

Multiple Sclerosis Hypertension

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

SVG PNG

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SMILES

CC(=O)O.N=C(N)N/N=C/c1c(Cl)cccc1Cl

InChI

InChI=1S/C8H8Cl2N4.C2H4O2/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12;1-2(3)4/h1-4H,(H4,11,12,14);1H3,(H,3,4)/b13-4+;

Molecular Formula

C10H12Cl2N4O2

HBD / HBA

3 / 4

회전 가능 결합

2

무거운 원자

18

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

The acetate salt form of guanabenz, a centrally acting antihypertensive that reduces blood pressure by stimulating alpha-2 receptors in the brainstem to decrease sympathetic nervous system activity. This formulation is used in oral tablet preparations for managing hypertension. Gradual dose reduction is important when stopping treatment to prevent rebound high blood pressure.

Yes, Guanabenz Acetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200560. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5702062. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

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Guanabenz Acetate PillFYI에서

구조

핵심 데이터

분자식: C10H12Cl2N4O2
동의어: 1

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의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.