Guanabenz Acetate

CHEMBL1200560 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

291.1 g/mol

LogP

—

Phase

4

The acetate salt form of guanabenz, a centrally acting antihypertensive that reduces blood pressure by stimulating alpha-2 receptors in the brainstem to decrease sympathetic nervous system activity. This formulation is used in oral tablet preparations for managing hypertension. Gradual dose reduction is important when stopping treatment to prevent rebound high blood pressure.

Peso Molecular

291,1300 g/mol

TPSA

114,00 Å²

Áreas Terapêuticas

Multiple Sclerosis Hypertension

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

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SMILES

CC(=O)O.N=C(N)N/N=C/c1c(Cl)cccc1Cl

InChI

InChI=1S/C8H8Cl2N4.C2H4O2/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12;1-2(3)4/h1-4H,(H4,11,12,14);1H3,(H,3,4)/b13-4+;

Molecular Formula

C10H12Cl2N4O2

HBD / HBA

3 / 4

Ligações Rotacionáveis

2

Átomos Pesados

18

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

The acetate salt form of guanabenz, a centrally acting antihypertensive that reduces blood pressure by stimulating alpha-2 receptors in the brainstem to decrease sympathetic nervous system activity. This formulation is used in oral tablet preparations for managing hypertension. Gradual dose reduction is important when stopping treatment to prevent rebound high blood pressure.

Yes, Guanabenz Acetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200560. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5702062. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

Procura informações acessíveis para o paciente?

Guanabenz Acetate no PillFYI

Estrutura

Dados Rápidos

Fórmula: C10H12Cl2N4O2
Sinônimos: 1

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.