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Hydromorphone Hydrochloride

CHEMBL1237055 Phase 4 승인됨 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
321.8 g/mol
LogP
—
Phase
4

A hydrochloride salt form of hydromorphone, a strong opioid pain reliever used for the management of moderate to severe pain when other analgesics are inadequate. The hydrochloride form is the standard pharmaceutical preparation used in tablets, injectable solutions, and extended-release capsules. As with all potent opioids, risk of respiratory depression, dependence, and misuse must be carefully managed.

분자량

321.8000 g/mol

TPSA

49.80 Ų

치료 영역

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Pain Management Non-Small Cell Lung Cancer Chronic Obstructive Pulmonary Disease Migraine Obesity Hypertension Breast Cancer Chronic Pain Prostate Cancer Colorectal Cancer Leukemia

작용 기전

Semisynthetic mu-opioid receptor agonist approximately 5 times more potent than morphine.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

기전

Semisynthetic mu-opioid receptor agonist approximately 5 times more potent than morphine.

2D 구조

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@H]3[C@H]1C5.Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C17H19NO3.ClH/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18;/h2,4,10-11,16,19H,3,5-8H2,1H3;1H/t10-,11+,16-,17-;/m0./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C17H20ClNO3

                    

                    
                    

                        
HBD / HBA

                        
2 / 4

                    

                    
                    

                        
회전 가능 결합

                        
0

                    

                    
                    
                    

                        
무거운 원자

                        
22

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
자주 묻는 질문

                

                    
                    

                        
                        

                            
A hydrochloride salt form of hydromorphone, a strong opioid pain reliever used for the management of moderate to severe pain when other analgesics are inadequate. The hydrochloride form is the standard pharmaceutical preparation used in tablets, injectable solutions, and extended-release capsules. As with all potent opioids, risk of respiratory depression, dependence, and misuse must be carefully managed.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Semisynthetic mu-opioid receptor agonist approximately 5 times more potent than morphine.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Hydromorphone Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1237055.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5462347.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
의학적 면책조항

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.