Levoketoconazole

CHEMBL295698 Phase 4 승인됨 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

531.4 g/mol

LogP

4.3

Phase

4

This medication is used to treat Cushing's syndrome, a condition caused by excess cortisol in the body, by blocking the enzymes that produce cortisol in the adrenal glands. It is the active enantiomer of ketoconazole, designed specifically to lower cortisol levels while reducing some of the side effects associated with the parent compound.

분자량

531.4000 g/mol

LogP

4.30

TPSA

69.10 Å²

리핀스키 5의 법칙

통과

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

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SMILES

CC(=O)N1CCN(c2ccc(OC[C@@H]3CO[C@@](Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1

InChI

InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1

Molecular Formula

C26H28Cl2N4O4

HBD / HBA

- / 6

회전 가능 결합

7

무거운 원자

36

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

This medication is used to treat Cushing's syndrome, a condition caused by excess cortisol in the body, by blocking the enzymes that produce cortisol in the adrenal glands. It is the active enantiomer of ketoconazole, designed specifically to lower cortisol levels while reducing some of the side effects associated with the parent compound.

Yes, Levoketoconazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL295698. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 47576. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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핵심 데이터

분자식: C26H28Cl2N4O4
동의어: 1

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의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.