Pentetate Indium Disodium In 111
A radioactive imaging agent in which indium-111 is chelated by DTPA, used in nuclear medicine to image cerebrospinal fluid spaces (cisternography) and evaluate CSF leaks or hydrocephalus. It is instilled intrathecally and its distribution is tracked by gamma camera imaging.
분자량
545.1900 g/mol
TPSA
210.00 Ų
작용 기전
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
SMILES
C(CN(CC(=O)[O-])CC(=O)[O-])N(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[111In+3]
InChI
InChI=1S/C14H23N3O10.In.2Na/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;;;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);;;/q;+3;2*+1/p-5/i;1-4;;
Molecular Formula
C14H18InN3Na2O10
HBD / HBA
- / 13
회전 가능 결합
11
무거운 원자
30
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
자주 묻는 질문
A radioactive imaging agent in which indium-111 is chelated by DTPA, used in nuclear medicine to image cerebrospinal fluid spaces (cisternography) and evaluate CSF leaks or hydrocephalus. It is instilled intrathecally and its distribution is tracked by gamma camera imaging.
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Yes, Pentetate Indium Disodium In 111 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2107480. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 23724985. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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