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Sulfacetamide

CHEMBL455 Phase 4 승인됨 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
214.2 g/mol
LogP
-1.0
Phase
4

Sulfacetamide is a sulfonamide antibiotic used topically in ophthalmic preparations for bacterial conjunctivitis and blepharitis caused by susceptible organisms, and in dermatological preparations for seborrheic dermatitis, rosacea, and acne. By inhibiting bacterial dihydropteroate synthase, it prevents folic acid synthesis in susceptible gram-positive and gram-negative bacteria. Its ophthalmic use is well established due to adequate corneal penetration and a favorable safety profile.

분자량

214.2400 g/mol

LogP

-1.00

TPSA

97.60 Ų

리핀스키 5의 법칙

통과

작용 기전

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

기전

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

2D 구조

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC(=O)NS(=O)(=O)c1ccc(N)cc1

                

                

                
                

                    
InChI

                    
InChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)

                

                

                

                    
                    

                        
Molecular Formula

                        
C8H10N2O3S

                    

                    
                    

                        
HBD / HBA

                        
2 / 4

                    

                    
                    

                        
회전 가능 결합

                        
2

                    

                    
                    
                    

                        
무거운 원자

                        
14

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
자주 묻는 질문

                

                    
                    

                        
                        

                            
Sulfacetamide is a sulfonamide antibiotic used topically in ophthalmic preparations for bacterial conjunctivitis and blepharitis caused by susceptible organisms, and in dermatological preparations for seborrheic dermatitis, rosacea, and acne. By inhibiting bacterial dihydropteroate synthase, it prevents folic acid synthesis in susceptible gram-positive and gram-negative bacteria. Its ophthalmic use is well established due to adequate corneal penetration and a favorable safety profile.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Sulfacetamide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL455.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5320.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
의학적 면책조항

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.