Sulfapyridine
Sulfapyridine is a sulfonamide antibacterial used as an active metabolite of sulfasalazine and independently for the treatment of dermatitis herpetiformis and linear IgA bullous dermatosis, where it suppresses neutrophil-mediated cutaneous inflammation. Sulfasalazine is cleaved in the colon by bacteria to release mesalazine (anti-inflammatory) and sulfapyridine, the carrier that ensures colonic delivery. In dermatitis herpetiformis, its anti-inflammatory mechanism likely involves suppression of neutrophil chemotaxis and oxidative burst.
분자량
249.2900 g/mol
LogP
0.00
TPSA
93.50 Ų
리핀스키 5의 법칙
통과
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D 구조
Cite this structure
Embed this structure
SMILES
Nc1ccc(S(=O)(=O)Nc2ccccn2)cc1
InChI
InChI=1S/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14)
Molecular Formula
C11H11N3O2S
HBD / HBA
2 / 5
회전 가능 결합
3
무거운 원자
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
자주 묻는 질문
Sulfapyridine is a sulfonamide antibacterial used as an active metabolite of sulfasalazine and independently for the treatment of dermatitis herpetiformis and linear IgA bullous dermatosis, where it suppresses neutrophil-mediated cutaneous inflammation. Sulfasalazine is cleaved in the colon by bacteria to release mesalazine (anti-inflammatory) and sulfapyridine, the carrier that ensures colonic delivery. In dermatitis herpetiformis, its anti-inflammatory mechanism likely involves suppression of neutrophil chemotaxis and oxidative burst.
Yes, Sulfapyridine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL700. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5336. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="sulfapyridine"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/sulfapyridine/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/sulfapyridine/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/sulfapyridine/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="sulfapyridine"></drugfyi-drug>