Viomycin

CHEMBL3085436 Phase 4 승인됨 Protein
Half-Life
Bioavailability
Protein Binding
Molecular Weight
685.7 g/mol
LogP
-7.0
Phase
4

Viomycin is a cyclic peptide antibiotic produced by Streptomyces species that inhibits bacterial protein synthesis by binding to the 30S and 50S ribosomal subunits and blocking translocation, with particular activity against mycobacteria including Mycobacterium tuberculosis. It was used as a second-line antituberculosis agent for drug-resistant TB before the development of modern combination regimens. Its nephrotoxicity and ototoxicity limit its clinical application.

분자량

685.7000 g/mol

LogP

-7.00

TPSA

393.00 Ų

리핀스키 5의 법칙

불통과

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

SVG PNG

Cite this structure


                        

Embed this structure


                        

SMILES

NCCC[C@H](N)CC(=O)N[C@H]1CNC(=O)[C@H]([C@H]2C[C@H](O)NC(N)=N2)NC(=O)/C(=C/NC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC1=O

InChI

InChI=1S/C25H43N13O10/c26-3-1-2-10(27)4-16(41)32-12-6-30-23(47)18(11-5-17(42)37-24(28)36-11)38-20(44)13(7-31-25(29)48)33-21(45)14(8-39)35-22(46)15(9-40)34-19(12)43/h7,10-12,14-15,17-18,39-40,42H,1-6,8-9,26-27H2,(H,30,47)(H,32,41)(H,33,45)(H,34,43)(H,35,46)(H,38,44)(H3,28,36,37)(H3,29,31,48)/b13-7-/t10-,11+,12-,14-,15-,17-,18-/m0/s1

Molecular Formula

C25H43N13O10

HBD / HBA

15 / 13

회전 가능 결합

10

무거운 원자

48

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

Viomycin is a cyclic peptide antibiotic produced by Streptomyces species that inhibits bacterial protein synthesis by binding to the 30S and 50S ribosomal subunits and blocking translocation, with particular activity against mycobacteria including Mycobacterium tuberculosis. It was used as a second-line antituberculosis agent for drug-resistant TB before the development of modern combination regimens. Its nephrotoxicity and ototoxicity limit its clinical application.

Yes, Viomycin is an approved drug. It has reached clinical phase 4. It is classified as a Protein.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3085436. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 135398671. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.