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Vonicog Alfa

CHEMBL2107873 Phase 4 승인됨 Protein
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
— g/mol
LogP
—
Phase
4

Vonicog alfa is a recombinant von Willebrand factor produced in Chinese hamster ovary cells that replaces or supplements endogenous VWF in patients with von Willebrand disease (VWD), restoring platelet adhesion to subendothelial collagen and stabilizing coagulation factor VIII from premature degradation. It is used for the treatment and prophylaxis of bleeding episodes in adults with severe type 3 VWD when desmopressin (DDAVP) treatment alone is ineffective or contraindicated. Its recombinant origin avoids the risk of viral transmission associated with plasma-derived VWF products.

작용 기전

As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

기전

As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

Vonicog alfa is a recombinant von Willebrand factor produced in Chinese hamster ovary cells that replaces or supplements endogenous VWF in patients with von Willebrand disease (VWD), restoring platelet adhesion to subendothelial collagen and stabilizing coagulation factor VIII from premature degradation. It is used for the treatment and prophylaxis of bleeding episodes in adults with severe type 3 VWD when desmopressin (DDAVP) treatment alone is ineffective or contraindicated. Its recombinant origin avoids the risk of viral transmission associated with plasma-derived …

As a recombinant protein, it replicates the function of the naturally occurring human protein, supplementing or replacing deficient endogenous production to restore normal physiological activity.

Yes, Vonicog Alfa is an approved drug. It has reached clinical phase 4. It is classified as a Protein.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2107873. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.