Number Needed to Harm (NNH)

NNH
Clinical

The number of patients exposed to a drug for one additional patient to experience an adverse event compared to control. Calculated as 1/absolute risk increase (ARI). Higher NNH indicates better safety.

예시

  • Comparing NNT/NNH for risk-benefit
  • NNH for GI bleeding with NSAIDs
  • Ideal NNH = infinity

알고 계셨나요?

The number of patients exposed to a drug for one additional patient to experience an adverse event compared to control. Calculated as 1/absolute risk increase (ARI). Higher NNH indicates better …