EGFR (Epidermal Growth Factor Receptor)
EGFR
Receptor tyrosine kinase driving cell proliferation, commonly mutated in NSCLC.
기능
Activating mutations drive oncogenic signaling. Targeted by TKIs (erlotinib, osimertinib) and antibodies (cetuximab).
이 표적에 작용하는 약물
| 약물 | 작용 | 주요 |
|---|---|---|
| Trastuzumab | Antagonist | 예 |