Aflibercept
A protein that works as a trap to capture vascular endothelial growth factor (VEGF), a substance that stimulates abnormal blood vessel growth in conditions like wet macular degeneration and certain cancers. By blocking VEGF, it helps prevent the leaky, abnormal vessels that can damage vision or feed tumor growth.
Áreas Terapêuticas
Mecanismo de Ação
Inhibits vascular endothelial growth factor (VEGF) signaling, blocking angiogenesis (new blood vessel formation) that tumors require for growth and metastasis.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits vascular endothelial growth factor (VEGF) signaling, blocking angiogenesis (new blood vessel formation) that tumors require for growth and metastasis.
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
A protein that works as a trap to capture vascular endothelial growth factor (VEGF), a substance that stimulates abnormal blood vessel growth in conditions like wet macular degeneration and certain cancers. By blocking VEGF, it helps prevent the leaky, abnormal vessels that can damage vision or feed tumor growth.
Inhibits vascular endothelial growth factor (VEGF) signaling, blocking angiogenesis (new blood vessel formation) that tumors require for growth and metastasis.
Yes, Aflibercept is an approved drug. It has reached clinical phase 4. It is classified as a Protein.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1742982. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="aflibercept"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/aflibercept/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/aflibercept/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/aflibercept/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="aflibercept"></drugfyi-drug>