Altretamine
An oral alkylating-like antineoplastic agent used to treat ovarian cancer that has persisted or recurred after standard platinum-based chemotherapy, though its precise mechanism is not fully understood. It disrupts cancer cell metabolism and DNA function, providing an option for patients whose disease has become resistant to other treatments.
Peso Molecular
210,2800 g/mol
LogP
2,70
TPSA
48,40 Ų
Regra dos 5 de Lipinski
Aprovado
Áreas Terapêuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estrutura 2D
Cite this structure
Embed this structure
SMILES
CN(C)c1nc(N(C)C)nc(N(C)C)n1
InChI
InChI=1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3
Molecular Formula
C9H18N6
HBD / HBA
- / 6
Ligações Rotacionáveis
3
Átomos Pesados
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
An oral alkylating-like antineoplastic agent used to treat ovarian cancer that has persisted or recurred after standard platinum-based chemotherapy, though its precise mechanism is not fully understood. It disrupts cancer cell metabolism and DNA function, providing an option for patients whose disease has become resistant to other treatments.
Yes, Altretamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1455. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2123. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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