Amodiaquine Hydrochloride

CHEMBL1357648 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

464.8 g/mol

LogP

—

Phase

4

The hydrochloride salt of amodiaquine, used in antimalarial combination therapies particularly in Africa. Liver toxicity with long-term use limits its application to short-course treatments.

Peso Molecular

464,8000 g/mol

TPSA

50,40 Å²

Áreas Terapêuticas

Malaria HIV/AIDS

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

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SMILES

CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O.Cl.Cl.O.O

InChI

InChI=1S/C20H22ClN3O.2ClH.2H2O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19;;;;/h5-12,25H,3-4,13H2,1-2H3,(H,22,23);2*1H;2*1H2

Molecular Formula

C20H28Cl3N3O3

HBD / HBA

6 / 6

Ligações Rotacionáveis

6

Átomos Pesados

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

The hydrochloride salt of amodiaquine, used in antimalarial combination therapies particularly in Africa. Liver toxicity with long-term use limits its application to short-course treatments.

Yes, Amodiaquine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1357648. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 64646. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

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Amodiaquine Hydrochloride no PillFYI

Estrutura

Dados Rápidos

Fórmula: C20H28Cl3N3O3

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.