Benzgalantamine
A prodrug of galantamine, an acetylcholinesterase inhibitor used in Alzheimer's disease that works by preventing the breakdown of acetylcholine in the brain, improving memory and cognitive function.
Peso Molecular
391,5000 g/mol
LogP
4,10
TPSA
48,00 Ų
Regra dos 5 de Lipinski
Aprovado
Mecanismo de Ação
Inhibits acetylcholinesterase, the enzyme that hydrolyzes acetylcholine in the synaptic cleft. This increases acetylcholine availability at cholinergic synapses, enhancing cholinergic neurotransmission.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits acetylcholinesterase, the enzyme that hydrolyzes acetylcholine in the synaptic cleft. This increases acetylcholine availability at cholinergic synapses, enhancing cholinergic neurotransmission.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
COc1ccc2c3c1O[C@H]1C[C@@H](OC(=O)c4ccccc4)C=C[C@@]31CCN(C)C2
InChI
InChI=1S/C24H25NO4/c1-25-13-12-24-11-10-18(28-23(26)16-6-4-3-5-7-16)14-20(24)29-22-19(27-2)9-8-17(15-25)21(22)24/h3-11,18,20H,12-15H2,1-2H3/t18-,20-,24-/m0/s1
Molecular Formula
C24H25NO4
HBD / HBA
- / 5
Ligações Rotacionáveis
4
Átomos Pesados
29
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
A prodrug of galantamine, an acetylcholinesterase inhibitor used in Alzheimer's disease that works by preventing the breakdown of acetylcholine in the brain, improving memory and cognitive function.
Inhibits acetylcholinesterase, the enzyme that hydrolyzes acetylcholine in the synaptic cleft. This increases acetylcholine availability at cholinergic synapses, enhancing cholinergic neurotransmission.
Yes, Benzgalantamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL5095056. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 44240142. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="benzgalantamine"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/benzgalantamine/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/benzgalantamine/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/benzgalantamine/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="benzgalantamine"></drugfyi-drug>