Bimatoprost
A prostaglandin analogue used as eye drops to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It works by increasing the drainage of fluid from the eye. It is also used in a topical formulation to stimulate eyelash growth.
Peso Molecular
415,6000 g/mol
LogP
2,80
TPSA
89,80 Ų
Regra dos 5 de Lipinski
Aprovado
Áreas Terapêuticas
Mecanismo de Ação
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
CCNC(=O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCc2ccccc2)[C@H](O)C[C@@H]1O
InChI
InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1
Molecular Formula
C25H37NO4
HBD / HBA
4 / 4
Ligações Rotacionáveis
12
Átomos Pesados
30
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
A prostaglandin analogue used as eye drops to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It works by increasing the drainage of fluid from the eye. It is also used in a topical formulation to stimulate eyelash growth.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Bimatoprost is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200963. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5311027. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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