Calcium Chloride
An injectable calcium salt used in emergency medicine to treat severe hypocalcemia, hyperkalemia, and calcium channel blocker overdose. It provides a higher concentration of elemental calcium per volume than calcium gluconate, making it preferred in critical settings. Extravasation can cause severe tissue damage, requiring careful intravenous administration.
Peso Molecular
110,9800 g/mol
TPSA
0,00 Ų
Áreas Terapêuticas
Mecanismo de Ação
Blocks L-type voltage-gated calcium channels in vascular smooth muscle and cardiac myocytes, reducing calcium influx during depolarization. This produces vasodilation, decreased myocardial contractility, and reduced heart rate.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Blocks L-type voltage-gated calcium channels in vascular smooth muscle and cardiac myocytes, reducing calcium influx during depolarization. This produces vasodilation, decreased myocardial contractility, and reduced heart rate.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
[Ca+2].[Cl-].[Cl-]
InChI
InChI=1S/Ca.2ClH/h;2*1H/q+2;;/p-2
Molecular Formula
CaCl2
HBD / HBA
- / 2
Ligações Rotacionáveis
0
Átomos Pesados
3
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
An injectable calcium salt used in emergency medicine to treat severe hypocalcemia, hyperkalemia, and calcium channel blocker overdose. It provides a higher concentration of elemental calcium per volume than calcium gluconate, making it preferred in critical settings. Extravasation can cause severe tissue damage, requiring careful intravenous administration.
Blocks L-type voltage-gated calcium channels in vascular smooth muscle and cardiac myocytes, reducing calcium influx during depolarization. This produces vasodilation, decreased myocardial contractility, and reduced heart rate.
Yes, Calcium Chloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200668. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5284359. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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