Carbidopa Anhydrous
The anhydrous form of carbidopa is used in combination with levodopa to manage the symptoms of Parkinson's disease, including tremors, stiffness, and slowness of movement. By inhibiting peripheral dopa decarboxylase, it increases the availability of levodopa in the brain. This form is chemically equivalent to the hydrated form but contains no bound water molecules.
Peso Molecular
226,2300 g/mol
LogP
-2,20
TPSA
116,00 Ų
Regra dos 5 de Lipinski
Aprovado
Áreas Terapêuticas
Mecanismo de Ação
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
C[C@@](Cc1ccc(O)c(O)c1)(NN)C(=O)O
InChI
InChI=1S/C10H14N2O4/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6/h2-4,12-14H,5,11H2,1H3,(H,15,16)/t10-/m0/s1
Molecular Formula
C10H14N2O4
HBD / HBA
5 / 6
Ligações Rotacionáveis
4
Átomos Pesados
16
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
The anhydrous form of carbidopa is used in combination with levodopa to manage the symptoms of Parkinson's disease, including tremors, stiffness, and slowness of movement. By inhibiting peripheral dopa decarboxylase, it increases the availability of levodopa in the brain. This form is chemically equivalent to the hydrated form but contains no bound water molecules.
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Yes, Carbidopa Anhydrous is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201236. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 34359. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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