Chenodiol

CHEMBL240597 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

392.6 g/mol

LogP

4.9

Phase

4

A naturally occurring bile acid that dissolves cholesterol gallstones in patients who are poor surgical candidates, by reducing biliary cholesterol saturation. It is also approved for the treatment of cerebrotendinous xanthomatosis, a rare inborn error of bile acid synthesis. Treatment may take months to years and is effective only for radiolucent, cholesterol-rich stones.

Peso Molecular

392,6000 g/mol

LogP

4,90

TPSA

77,80 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Hyperlipidemia Obesity Type 2 Diabetes Atopic Dermatitis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

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SMILES

C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

Molecular Formula

C24H40O4

HBD / HBA

3 / 4

Ligações Rotacionáveis

4

Átomos Pesados

28

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

A naturally occurring bile acid that dissolves cholesterol gallstones in patients who are poor surgical candidates, by reducing biliary cholesterol saturation. It is also approved for the treatment of cerebrotendinous xanthomatosis, a rare inborn error of bile acid synthesis. Treatment may take months to years and is effective only for radiolucent, cholesterol-rich stones.

Yes, Chenodiol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL240597. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 10133. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

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Chenodiol no PillFYI

Estrutura

Dados Rápidos

Fórmula: C24H40O4
Sinônimos: 2

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.