Chymopapain

CHEMBL1201626 Phase 4 Aprovado Unknown

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

— g/mol

LogP

—

Phase

4

A proteolytic enzyme derived from the papaya plant previously used by intradiscal injection for chemonucleolysis, a non-surgical treatment for herniated lumbar intervertebral discs. It works by dissolving the proteoglycan component of the nucleus pulposus, relieving disc pressure on the nerve. It was withdrawn from the US market due to serious allergic reactions including anaphylaxis and rare neurological complications.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

A proteolytic enzyme derived from the papaya plant previously used by intradiscal injection for chemonucleolysis, a non-surgical treatment for herniated lumbar intervertebral discs. It works by dissolving the proteoglycan component of the nucleus pulposus, relieving disc pressure on the nerve. It was withdrawn from the US market due to serious allergic reactions including anaphylaxis and rare neurological complications.

Yes, Chymopapain is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201626. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

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Dados Rápidos

Links Externos

ChEMBL CHEMBL1201626

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.