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Clioquinol

CHEMBL497 Phase 4 Aprovado Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
305.5 g/mol
LogP
3.5
Phase
4

A halogenated hydroxyquinoline with both antifungal and antibacterial properties once widely used for skin infections and traveler's diarrhea. Its systemic use was largely abandoned after links to subacute myelo-optic neuropathy, though topical application remains in some formulations.

Peso Molecular

305,5000 g/mol

LogP

3,50

TPSA

33,10 Ų

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Epilepsy Psoriasis Lymphoma Leukemia

Mecanismo de Ação

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mecanismo

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Estrutura 2D

SVG PNG

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SMILES

                    
Oc1c(I)cc(Cl)c2cccnc12

                

                

                
                

                    
InChI

                    
InChI=1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H

                

                

                

                    
                    

                        
Molecular Formula

                        
C9H5ClINO

                    

                    
                    

                        
HBD / HBA

                        
1 / 2

                    

                    
                    

                        
Ligações Rotacionáveis

                        
0

                    

                    
                    
                    

                        
Átomos Pesados

                        
13

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Perguntas frequentes

                

                    
                    

                        
                        

                            
A halogenated hydroxyquinoline with both antifungal and antibacterial properties once widely used for skin infections and traveler's diarrhea. Its systemic use was largely abandoned after links to subacute myelo-optic neuropathy, though topical application remains in some formulations.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Clioquinol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL497.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2788.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Aviso Médico

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.