Clonidine Hydrochloride

CHEMBL1705 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

266.6 g/mol

LogP

—

Phase

4

The hydrochloride salt of clonidine, used to treat high blood pressure, ADHD, and symptoms of opioid or nicotine withdrawal by reducing nervous system activity. The salt form is stable and well-absorbed when taken orally.

Peso Molecular

266,6000 g/mol

TPSA

36,40 Å²

Áreas Terapêuticas

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Endometriosis Cardiovascular Disease Pain Management Non-Small Cell Lung Cancer Parkinson's Disease Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Obstetrics & Gynecology Chronic Kidney Disease Stroke Obesity Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer Chronic Pain Heart Failure Prostate Cancer Colorectal Cancer

Mecanismo de Ação

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mecanismo

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …

Estrutura 2D

SVG PNG

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SMILES

Cl.Clc1cccc(Cl)c1NC1=NCCN1

InChI

InChI=1S/C9H9Cl2N3.ClH/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9;/h1-3H,4-5H2,(H2,12,13,14);1H

Molecular Formula

C9H10Cl3N3

HBD / HBA

3 / 1

Ligações Rotacionáveis

2

Átomos Pesados

15

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

The hydrochloride salt of clonidine, used to treat high blood pressure, ADHD, and symptoms of opioid or nicotine withdrawal by reducing nervous system activity. The salt form is stable and well-absorbed when taken orally.

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Yes, Clonidine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1705. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 20179. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

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Estrutura

Dados Rápidos

Fórmula: C9H10Cl3N3
Sinônimos: 3

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.