Danazol

CHEMBL1479 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

337.5 g/mol

LogP

3.8

Phase

4

A synthetic androgen derived from ethisterone that suppresses pituitary gonadotropins, used to treat endometriosis, fibrocystic breast disease, and hereditary angioedema. Its androgenic side effects including acne, voice changes, and liver toxicity have limited its use.

Peso Molecular

337,5000 g/mol

LogP

3,80

TPSA

46,30 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Endometriosis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

C#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=Cc5oncc5C[C@]4(C)[C@H]3CC[C@@]21C

InChI

InChI=1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16-,17+,18+,20+,21+,22+/m1/s1

Molecular Formula

C22H27NO2

HBD / HBA

1 / 3

Ligações Rotacionáveis

1

Átomos Pesados

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

A synthetic androgen derived from ethisterone that suppresses pituitary gonadotropins, used to treat endometriosis, fibrocystic breast disease, and hereditary angioedema. Its androgenic side effects including acne, voice changes, and liver toxicity have limited its use.

Yes, Danazol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1479. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 28417. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

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Danazol no PillFYI

Estrutura

Dados Rápidos

Fórmula: C22H27NO2

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.