Dexfenfluramine Hydrochloride

CHEMBL1887891 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

267.7 g/mol

LogP

—

Phase

4

The hydrochloride salt form of dexfenfluramine, the more active isomer of the appetite-suppressant fenfluramine, used briefly in obesity treatment before being withdrawn from the market. It caused serious heart valve abnormalities and pulmonary hypertension. It is no longer used clinically.

Peso Molecular

267,7200 g/mol

TPSA

12,00 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

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SMILES

CCN[C@@H](C)Cc1cccc(C(F)(F)F)c1.Cl

InChI

InChI=1S/C12H16F3N.ClH/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15;/h4-6,8-9,16H,3,7H2,1-2H3;1H/t9-;/m0./s1

Molecular Formula

C12H17ClF3N

HBD / HBA

2 / 4

Ligações Rotacionáveis

4

Átomos Pesados

17

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

The hydrochloride salt form of dexfenfluramine, the more active isomer of the appetite-suppressant fenfluramine, used briefly in obesity treatment before being withdrawn from the market. It caused serious heart valve abnormalities and pulmonary hypertension. It is no longer used clinically.

Yes, Dexfenfluramine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1887891. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 66264. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

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Dexfenfluramine Hydrochloride no PillFYI

Estrutura

Dados Rápidos

Fórmula: C12H17ClF3N

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.