Dextromethorphan Hydrobromide

CHEMBL1256818 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

352.3 g/mol

LogP

—

Phase

4

The hydrobromide salt form of dextromethorphan, the most common form found in cough preparations. It suppresses coughing centrally and is combined with various other ingredients in multi-symptom cold and flu remedies.

Peso Molecular

352,3000 g/mol

TPSA

12,50 Å²

Áreas Terapêuticas

Pain Management Rheumatoid Arthritis Alzheimer's Disease Parkinson's Disease Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Melanoma Psoriasis Multiple Sclerosis Stroke Obesity Lymphoma Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer Chronic Pain Malaria Tuberculosis Prostate Cancer Leukemia

Mecanismo de Ação

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mecanismo

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …

Estrutura 2D

SVG PNG

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SMILES

Br.COc1ccc2c(c1)[C@]13CCCC[C@@H]1[C@H](C2)N(C)CC3.O

InChI

InChI=1S/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15-,17+,18+;;/m1../s1

Molecular Formula

C18H26BrNO

HBD / HBA

1 / 2

Ligações Rotacionáveis

1

Átomos Pesados

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

The hydrobromide salt form of dextromethorphan, the most common form found in cough preparations. It suppresses coughing centrally and is combined with various other ingredients in multi-symptom cold and flu remedies.

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Yes, Dextromethorphan Hydrobromide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1256818. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5464025. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Estrutura

Dados Rápidos

Fórmula: C18H26BrNO
Sinônimos: 920

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.