Fluorometholone
This topical ophthalmic corticosteroid is used to treat inflammatory conditions of the eye, including allergic conjunctivitis and post-surgical inflammation. It has a lower risk of raising intraocular pressure compared to some other eye corticosteroids, making it preferred for certain inflammatory eye conditions.
Peso Molecular
376,5000 g/mol
LogP
2,00
TPSA
74,60 Ų
Regra dos 5 de Lipinski
Aprovado
Áreas Terapêuticas
Mecanismo de Ação
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
InChI
InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1
Molecular Formula
C22H29FO4
HBD / HBA
2 / 5
Ligações Rotacionáveis
1
Átomos Pesados
27
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
This topical ophthalmic corticosteroid is used to treat inflammatory conditions of the eye, including allergic conjunctivitis and post-surgical inflammation. It has a lower risk of raising intraocular pressure compared to some other eye corticosteroids, making it preferred for certain inflammatory eye conditions.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Fluorometholone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200600. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 9878. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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