Galantamine Hydrobromide
This hydrobromide salt form of galantamine is used to manage the cognitive and functional symptoms of mild to moderate Alzheimer's disease by boosting acetylcholine neurotransmission in the brain. It is taken orally and is one of the standard acetylcholinesterase inhibitors used in dementia care.
Peso Molecular
368,3000 g/mol
TPSA
41,90 Ų
Áreas Terapêuticas
Mecanismo de Ação
Inhibits acetylcholinesterase, the enzyme that hydrolyzes acetylcholine in the synaptic cleft. This increases acetylcholine availability at cholinergic synapses, enhancing cholinergic neurotransmission.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits acetylcholinesterase, the enzyme that hydrolyzes acetylcholine in the synaptic cleft. This increases acetylcholine availability at cholinergic synapses, enhancing cholinergic neurotransmission.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
Br.COc1ccc2c3c1O[C@H]1C[C@@H](O)C=C[C@@]31CCN(C)C2
InChI
InChI=1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1
Molecular Formula
C17H22BrNO3
HBD / HBA
2 / 4
Ligações Rotacionáveis
1
Átomos Pesados
22
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
This hydrobromide salt form of galantamine is used to manage the cognitive and functional symptoms of mild to moderate Alzheimer's disease by boosting acetylcholine neurotransmission in the brain. It is taken orally and is one of the standard acetylcholinesterase inhibitors used in dementia care.
Inhibits acetylcholinesterase, the enzyme that hydrolyzes acetylcholine in the synaptic cleft. This increases acetylcholine availability at cholinergic synapses, enhancing cholinergic neurotransmission.
Yes, Galantamine Hydrobromide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1555. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 121587. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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