Ganciclovir

CHEMBL182 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

255.2 g/mol

LogP

-2.5

Phase

4

This antiviral medication works by being converted inside virus-infected cells into a compound that blocks viral DNA polymerase, preventing cytomegalovirus from replicating. It is used to treat and prevent serious CMV infections, particularly in immunocompromised patients such as transplant recipients and those with HIV.

Peso Molecular

255,2300 g/mol

LogP

-2,50

TPSA

135,00 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Melanoma Inflammatory Bowel Disease Systemic Lupus Erythematosus Lymphoma Major Depressive Disorder Breast Cancer Malaria HIV/AIDS Tuberculosis Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

Cite this structure

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SMILES

Nc1nc2c(ncn2COC(CO)CO)c(=O)[nH]1

InChI

InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)

Molecular Formula

C9H13N5O4

HBD / HBA

4 / 6

Ligações Rotacionáveis

5

Átomos Pesados

18

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

This antiviral medication works by being converted inside virus-infected cells into a compound that blocks viral DNA polymerase, preventing cytomegalovirus from replicating. It is used to treat and prevent serious CMV infections, particularly in immunocompromised patients such as transplant recipients and those with HIV.

Yes, Ganciclovir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL182. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 135398740. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Estrutura

Dados Rápidos

Fórmula: C9H13N5O4
Sinônimos: 1

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.