Haloprogin
A topical antifungal agent used to treat superficial fungal infections of the skin including tinea pedis (athlete's foot), tinea cruris (jock itch), and tinea corporis (ringworm). It works by disrupting the fungal cell membrane, causing leakage of cellular contents. It has largely been replaced by newer antifungals with improved efficacy and tolerability.
Peso Molecular
361,4000 g/mol
LogP
4,60
TPSA
9,20 Ų
Regra dos 5 de Lipinski
Aprovado
Mecanismo de Ação
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
Clc1cc(Cl)c(OCC#CI)cc1Cl
InChI
InChI=1S/C9H4Cl3IO/c10-6-4-8(12)9(5-7(6)11)14-3-1-2-13/h4-5H,3H2
Molecular Formula
C9H4Cl3IO
HBD / HBA
- / 1
Ligações Rotacionáveis
2
Átomos Pesados
14
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
A topical antifungal agent used to treat superficial fungal infections of the skin including tinea pedis (athlete's foot), tinea cruris (jock itch), and tinea corporis (ringworm). It works by disrupting the fungal cell membrane, causing leakage of cellular contents. It has largely been replaced by newer antifungals with improved efficacy and tolerability.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Haloprogin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1289. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3561. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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